Class of 2021 undergraduate research team seeking to build and analyze models built for a specific toxicity endpoint of a drug and investigate what aspects of the process leads to the best performance.
The Problem
The current standard of drug evaluation is inefficient. Most substances are taken through clinical trials, which require the most time and money of the medical research process, only to be deemed unusable. The cost of developing and testing drugs combined with the high failure rate force the price and pace of medicine production to increase. Development of computer models built from experimental data help reduce the amount of drug candidates the move to clinical trials by predicting if a drug is not suitable for its application based on certain properties.
The Question
How can the process of developing a computer model of a drug be improved to increase the accuracy of toxicity prediction?
